Gene Function Prediction
Eisenhaber Frank
EISENHABER Frank Senior Fellow, Senior Principal Investigator Email: franke@bii.a-star.edu.sg Research Group: Gene Function Prediction |
Frank Eisenhaber studied at the Humboldt-University in Berlin, at the Pirogov Medical University in Moscow and received the PhD in molecular biology from the Engelhardt Institute of Molecular Biology in Moscow 1988. He worked at the EMBL in Heidelberg (1991-1999), at the Institute of Molecular Pathology (IMP) in Vienna (1999-2007) and at A*STAR Singapore (since 2007). During 2007-2020, he was the Executive Director of the Bioinformatics Institute of A*STAR. At present, he is a Senior Principal Investigator (GIS and BII) and A*STAR Senior Fellow. Frank Eisenhaber’s research interest is focused on the discovery of new biomolecular mechanisms from biological and medical data and the functional characterization of yet uncharacterized genes and pathways. Frank Eisenhaber is one of the scientists credited with the discovery of the SET domain methyltransferases, ATGL, kleisins, GPAA1 many new protein domain functions, with the development of accurate prediction tools for posttranslational modifications, subcellular localizations, with algorithms for omics data analysis and with the molecular surface routine NSC.
Research Interests
Frank Eisenhaber’s research interest is focused on the discovery of new biomolecular mechanisms from biological and medical data and the functional characterization of yet uncharacterized genes and pathways. As mechanistic insight is the driver for biotechnology, biomedical and clinical applications, this work has catalyzed various lines of applied research. Frank Eisenhaber is one of the scientists credited with the discovery of the SET domain methyltransferases, ATGL, kleisins, many new protein domain functions (for example in the GPI lipid anchor biosynthsis pathway), with the development of accurate prediction tools for posttranslational modifications and subcellular localizations and with algorithms for omics data analysis.
Group Members
Senior Principal Investigator | EISENHABER Birgit |
Assistant Principal Investigator | ALFATAH Mohammad |
Research Manager | TANTOSO Erwin |
Senior Bioinformatics Specialist | KUCHIBATHLA Durga |
Post-Doctoral Research Fellow | ARSHIA Naaz |
Eisenhaber Birgit
EISENHABER Birgit Senior Principal Investigator Email: birgite@bii.a-star.edu.sg Research Group: Gene Function Prediction |
Birgit Eisenhaber’s research interest is focused on the discovery of molecular functions of previously uncharacterized proteincoding genes with special focus in proteins’ posttranslational modifications. Her entry work into science was the discovery and quantitative description of motifs coding for lipid anchor modifications. Birgit Eisenhaber studied biocybernetics and medicine at the Pirogov Medical University in Moscow. After working as a professional software developer, she restarted her scientific career at the EMBL Heidelberg. She obtained her Ph.D. from Humboldt University Berlin. Subsequently, she worked as a postdoctoral research fellow at the Institute of Molecular Pathology (IMP) Vienna and at the Experimental Therapeutics Centre (ETC) Singapore. In December 2010, Birgit Eisenhaber was appointed as a teamleader. She is now a Senior Principal Investigator at the Genome Institute of Singapore (GIS) and at the Bioinformatics Institute (BII).
Research Interests
Birgit is part of the Gene Function Prediction group that is focused on the prediction of molecular and cellular functions of genes and proteins based on the theoretical analysis of biomolecular sequences, expression profiles and other omics high-throughput data.
Group Members
A*STAR Senior Fellow, Senior Principal Investigator | EISENHABER Frank |
Assistant Principal Investigator | ALFATAH Mohammad |
Research Manager | TANTOSO Erwin |
Senior Bioinformatics Specialist | KUCHIBATHLA Durga |
Post-Doctoral Research Fellow | ARSHIA Naaz |
A*STAR celebrates International Women's Day
From groundbreaking discoveries to cutting-edge research, our researchers are empowering the next generation of female science, technology, engineering and mathematics (STEM) leaders.
Get inspired by our #WomeninSTEM